proteindesign相关论文
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Discovery of covalent ligands via non-covalent docking by dissecting covalent docking based on a par
Covalent ligands modulating protein activities/signals have attracted unprecedented attention in recent years,but the in......
Amyloid fibrils play important roles in most neurodegenerative diseases like Parkinsons and Alzheimers diseases.Understa......
Motivation: Structure-based computational protein design is an important topic in protein engineering.Under the assumpti......
Background: The Tumor necrosis factor (TNF) is an established therapeutic target for rheumatoid arthritis and other auto......
Genome sequencing projects have revolutionized our view of the complexity of prokaryotic and eukaryotic proteomes,howeve......
Uranyl (UO22+), the predominant aerobic form of uranium, is present in the ocean at the concentration of~3.2 ppb (13.7 nM......
Approaches to degradation of industrial dyes are desirable,of which bioremediation is more favorable....
Computational Protein Design with a Comprehensive Statistical Energy Function and Boosted by an in v
The de novo design of amino acid sequences to fold into desired structures is a way to reach a more thorough underst......
Designing functional proteins is the ultimate test for our understandings of protein structure and function relation......
Metalloenzymes play important roles in numerous biological processes.Designing metalloenzymes is an ultimate test of......